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High CSF thrombin concentration and activity is associated with an unfavorable outcome in patients with intracerebral hemorrhage
BACKGROUND: The cerebral thrombin system is activated in the early stage after intracerebral hemorrhage (ICH). Expression of thrombin leads to concentration dependent secondary neuronal damage and detrimental neurological outcome. In this study we aimed to investigate the impact of thrombin concentr...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657554/ https://www.ncbi.nlm.nih.gov/pubmed/33175864 http://dx.doi.org/10.1371/journal.pone.0241565 |