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Chicoric Acid Ameliorates Nonalcoholic Fatty Liver Disease via the AMPK/Nrf2/NFκB Signaling Pathway and Restores Gut Microbiota in High-Fat-Diet-Fed Mice

This study examines the effects of chicoric acid (CA) on nonalcoholic fatty liver disease (NAFLD) in high-fat-diet- (HFD-) fed C57BL/6 mice. CA treatment decreased body weight and white adipose weight, mitigated hyperglycemia and dyslipidemia, and reduced hepatic steatosis in HFD-fed mice. Moreover,...

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Detalles Bibliográficos
Autores principales: Ding, Xiaoqin, Jian, Tunyu, Li, Jiawei, Lv, Han, Tong, Bei, Li, Jing, Meng, Xiuhua, Ren, Bingru, Chen, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657699/
https://www.ncbi.nlm.nih.gov/pubmed/33204402
http://dx.doi.org/10.1155/2020/9734560