Upstream development of Escherichia coli fermentation process with PhoA promoter using design of experiments (DoE)

In this work, a fed-batch fermentation development was performed with recombinant E. coli carrying the PhoA promoter system. The phosphate concentrations tested for this PhoA strain, 2.79 mM to 86.4 mM, were beyond the concentrations previously evaluated for cell growth and product titer. The result...

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Detalles Bibliográficos
Autores principales: Agbogbo, Frank K., Ramsey, Phil, George, Renija, Joy, Jobin, Srivastava, Shikha, Huang, Mian, McCool, Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Fermentation, Cell Culture and Bioengineering - Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658055/
https://www.ncbi.nlm.nih.gov/pubmed/32844325
http://dx.doi.org/10.1007/s10295-020-02302-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658055/
https://www.ncbi.nlm.nih.gov/pubmed/32844325
http://dx.doi.org/10.1007/s10295-020-02302-7

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