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Upstream development of Escherichia coli fermentation process with PhoA promoter using design of experiments (DoE)
In this work, a fed-batch fermentation development was performed with recombinant E. coli carrying the PhoA promoter system. The phosphate concentrations tested for this PhoA strain, 2.79 mM to 86.4 mM, were beyond the concentrations previously evaluated for cell growth and product titer. The result...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658055/ https://www.ncbi.nlm.nih.gov/pubmed/32844325 http://dx.doi.org/10.1007/s10295-020-02302-7 |