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The effects of HIF-1α overexpression on renal injury, immune disorders and mitochondrial apoptotic pathways in renal ischemia/reperfusion rats

BACKGROUND: Renal ischemia/reperfusion (RI/R) injury are a common pathogenesis of acute kidney injury, which may cause renal parenchyma damage clinically. Hypoxia-inducible factor-1α (HIF-1α) has protective effects on cells in regulating the metabolism, angiogenesis, erythropoiesis, and anti-apoptos...

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Detalles Bibliográficos
Autores principales: Li, Xiaoli, Chen, Wenhui, Feng, Jinfang, Zhao, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658158/
https://www.ncbi.nlm.nih.gov/pubmed/33209679
http://dx.doi.org/10.21037/tau-20-918