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A higher dose of vancomycin is needed in critically ill patients with augmented renal clearance

BACKGROUND: Using standard vancomycin dosage in critically ill patients might lead to therapy failure and worse patient outcomes, augmented renal clearance (ARC) may be the leading risk factor. In this study, we comprehensively investigated the pharmacokinetics-pharmacodynamics (PK-PD) of vancomycin...

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Detalles Bibliográficos
Autores principales: He, Juan, Yang, Zhi-Tao, Qian, Xian, Zhao, Bing, Mao, En-Qiang, Chen, Er-Zhen, Bian, Xiao-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658164/
https://www.ncbi.nlm.nih.gov/pubmed/33209680
http://dx.doi.org/10.21037/tau-20-1048