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TPP1 Enhances the Therapeutic Effects of Transplanted Aged Mesenchymal Stem Cells in Infarcted Hearts via the MRE11/AKT Pathway

BACKGROUND: Poor cell survival after transplantation restricts the therapeutic potential of mesenchymal stem cell (MSC) transplantation into infarcted hearts, particularly in older individuals. TPP1, a component of the shelterin complex that is involved in telomere protection, is highly expressed in...

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Detalles Bibliográficos
Autores principales: Yu, Kaixiang, Zeng, Zhiru, Cheng, Si, Hu, Wangxing, Gao, Chenyang, Liu, Feng, Chen, Jinyong, Qian, Yi, Xu, Dilin, Zhao, Jing, Liu, Xianbao, Wang, Jian’an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658181/
https://www.ncbi.nlm.nih.gov/pubmed/33195247
http://dx.doi.org/10.3389/fcell.2020.588023