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TPP1 Enhances the Therapeutic Effects of Transplanted Aged Mesenchymal Stem Cells in Infarcted Hearts via the MRE11/AKT Pathway
BACKGROUND: Poor cell survival after transplantation restricts the therapeutic potential of mesenchymal stem cell (MSC) transplantation into infarcted hearts, particularly in older individuals. TPP1, a component of the shelterin complex that is involved in telomere protection, is highly expressed in...
Autores principales: | Yu, Kaixiang, Zeng, Zhiru, Cheng, Si, Hu, Wangxing, Gao, Chenyang, Liu, Feng, Chen, Jinyong, Qian, Yi, Xu, Dilin, Zhao, Jing, Liu, Xianbao, Wang, Jian’an |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658181/ https://www.ncbi.nlm.nih.gov/pubmed/33195247 http://dx.doi.org/10.3389/fcell.2020.588023 |
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