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Dengue virus infection impedes megakaryopoiesis in MEG-01 cells where the virus envelope protein interacts with the transcription factor TAL-1

Dengue virus (DENV) infection causes dengue fever in humans, which can lead to thrombocytopenia showing a marked reduction in platelet counts, and dengue hemorrhagic fever. The virus may cause thrombocytopenia either by destroying the platelets or by interfering with their generation via the process...

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Detalles Bibliográficos
Autores principales: Banerjee, Atoshi, Tripathi, Aarti, Duggal, Shweta, Banerjee, Arup, Vrati, Sudhanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658202/
https://www.ncbi.nlm.nih.gov/pubmed/33177556
http://dx.doi.org/10.1038/s41598-020-76350-5