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Early-life stress alters affective behaviors in adult mice through persistent activation of CRH-BDNF signaling in the oval bed nucleus of the stria terminalis

Early-life stress (ELS) leads to stress-related psychopathology in adulthood. Although dysfunction of corticotropin-releasing hormone (CRH) signaling in the bed nucleus of the stria terminalis (BNST) mediates chronic stress-induced maladaptive affective behaviors that are historically associated wit...

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Detalles Bibliográficos
Autores principales: Hu, Pu, Maita, Isabella, Phan, Mimi L., Gu, Edward, Kwok, Christopher, Dieterich, Andrew, Gergues, Mark M., Yohn, Christine N., Wang, Yu, Zhou, Jiang-Ning, Qi, Xin-Rui, Swaab, Dick F., Pang, Zhiping P., Lucassen, Paul J., Roepke, Troy A., Samuels, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658214/
https://www.ncbi.nlm.nih.gov/pubmed/33177511
http://dx.doi.org/10.1038/s41398-020-01070-3