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Early-life stress alters affective behaviors in adult mice through persistent activation of CRH-BDNF signaling in the oval bed nucleus of the stria terminalis
Early-life stress (ELS) leads to stress-related psychopathology in adulthood. Although dysfunction of corticotropin-releasing hormone (CRH) signaling in the bed nucleus of the stria terminalis (BNST) mediates chronic stress-induced maladaptive affective behaviors that are historically associated wit...
Autores principales: | Hu, Pu, Maita, Isabella, Phan, Mimi L., Gu, Edward, Kwok, Christopher, Dieterich, Andrew, Gergues, Mark M., Yohn, Christine N., Wang, Yu, Zhou, Jiang-Ning, Qi, Xin-Rui, Swaab, Dick F., Pang, Zhiping P., Lucassen, Paul J., Roepke, Troy A., Samuels, Benjamin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658214/ https://www.ncbi.nlm.nih.gov/pubmed/33177511 http://dx.doi.org/10.1038/s41398-020-01070-3 |
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