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Oncogenic role of lncRNA CRNDE in acute promyelocytic leukemia and NPM1-mutant acute myeloid leukemia

The PML/RARα fusion protein acts in concert with cooperative genetic events in the development of acute promyelocytic leukemia (APL). However, oncogenic long non-coding RNAs (lncRNAs) cooperating with PML/RARα remain under-explored. Here, we first identified a set of pathogenesis-related lncRNAs, ab...

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Detalles Bibliográficos
Autores principales: Ma, Xuefei, Zhang, Wei, Zhao, Ming, Li, Shufen, Jin, Wen, Wang, Kankan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658230/
https://www.ncbi.nlm.nih.gov/pubmed/33298855
http://dx.doi.org/10.1038/s41420-020-00359-y