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Predicting antibody affinity changes upon mutations by combining multiple predictors

Antibodies are proteins working in our immune system with high affinity and specificity for target antigens, making them excellent tools for both biotherapeutic and bioengineering applications. The prediction of antibody affinity changes upon mutations ([Formula: see text] ) is important for antibod...

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Detalles Bibliográficos
Autores principales: Kurumida, Yoichi, Saito, Yutaka, Kameda, Tomoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658247/
https://www.ncbi.nlm.nih.gov/pubmed/33177627
http://dx.doi.org/10.1038/s41598-020-76369-8