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Drug Discovery and Development of Novel Therapeutics for Inhibiting TMAO in Models of Atherosclerosis and Diabetes

Diabetes mellitus exists as a comorbidity with congestive heart failure (CHF). However, the exact molecular signaling mechanism linking CHF as the major form of mortality from diabetes remains unknown. Type 2 diabetic patients display abnormally high levels of metabolic products associated with gut...

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Detalles Bibliográficos
Autores principales: Steinke, Ian, Ghanei, Nila, Govindarajulu, Manoj, Yoo, Sieun, Zhong, Juming, Amin, Rajesh H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658318/
https://www.ncbi.nlm.nih.gov/pubmed/33192565
http://dx.doi.org/10.3389/fphys.2020.567899