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The Dunkin Hartley Guinea Pig Is a Model of Primary Osteoarthritis That Also Exhibits Early Onset Myofiber Remodeling That Resembles Human Musculoskeletal Aging

Skeletal muscle dysfunction, articular cartilage degeneration, and bone loss occur essentially in parallel during aging. Mechanisms contributing to this systemic musculoskeletal decline remain incompletely understood, limiting progress toward developing effective therapeutics. Because the progressio...

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Detalles Bibliográficos
Autores principales: Musci, Robert V., Walsh, Maureen A., Konopka, Adam R., Wolff, Christopher A., Peelor, Frederick F., Reiser, Raoul F., Santangelo, Kelly S., Hamilton, Karyn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658338/
https://www.ncbi.nlm.nih.gov/pubmed/33192568
http://dx.doi.org/10.3389/fphys.2020.571372