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Distinct regional ontogeny and activation of tumor associated macrophages in human glioblastoma

Tumor-associated macrophages (TAMs) constitute up to 50% of tumor bulk in glioblastoma (GBM) and play an important role in tumor maintenance and progression. The recently discovered differences between invading tumour periphery and hypoxic tumor core implies that macrophage biology is also distinct...

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Detalles Bibliográficos
Autores principales: Landry, Alexander P., Balas, Michael, Alli, Saira, Spears, Julian, Zador, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658345/
https://www.ncbi.nlm.nih.gov/pubmed/33177572
http://dx.doi.org/10.1038/s41598-020-76657-3