The tumor suppressor microRNA let-7 inhibits human LINE-1 retrotransposition

Nearly half of the human genome is made of transposable elements (TEs) whose activity continues to impact its structure and function. Among them, Long INterspersed Element class 1 (LINE-1 or L1) elements are the only autonomously active TEs in humans. L1s are expressed and mobilized in different can...

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Detalles Bibliográficos
Autores principales: Tristán-Ramos, Pablo, Rubio-Roldan, Alejandro, Peris, Guillermo, Sánchez, Laura, Amador-Cubero, Suyapa, Viollet, Sebastien, Cristofari, Gael, Heras, Sara R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658363/
https://www.ncbi.nlm.nih.gov/pubmed/33177501
http://dx.doi.org/10.1038/s41467-020-19430-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658363/
https://www.ncbi.nlm.nih.gov/pubmed/33177501
http://dx.doi.org/10.1038/s41467-020-19430-4

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