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The tumor suppressor microRNA let-7 inhibits human LINE-1 retrotransposition
Nearly half of the human genome is made of transposable elements (TEs) whose activity continues to impact its structure and function. Among them, Long INterspersed Element class 1 (LINE-1 or L1) elements are the only autonomously active TEs in humans. L1s are expressed and mobilized in different can...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658363/ https://www.ncbi.nlm.nih.gov/pubmed/33177501 http://dx.doi.org/10.1038/s41467-020-19430-4 |