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Derivation and Differentiation of Adipose-Tissue Regulatory T Cells: A Stepwise, Multi-Site Process
CD4(+) Foxp3(+) regulatory T cells (Tregs) not only enforce peripheral tolerance and restrain self-reactive immune responses, but also maintain organismal homeostasis and safeguard the function of parenchymal tissues. A paradigmatic tissue–Treg population resides in the visceral adipose tissue (VAT)...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658365/ https://www.ncbi.nlm.nih.gov/pubmed/33193452 http://dx.doi.org/10.3389/fimmu.2020.599277 |