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The Synovium Attenuates Cartilage Degeneration in KOA through Activation of the Smad2/3-Runx1 Cascade and Chondrogenesis-related miRNAs

Knee osteoarthritis (KOA) is a highly prevalent disabling joint disease in aged people. Progressive cartilage degradation is the hallmark of KOA, but its deeper mechanism remains unclear. Substantial evidence indicates the importance of the synovium for joint homeostasis. The present study aimed to...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaoyi, Meng, Fangang, Hu, Shu, Yang, Zibo, Huang, Hao, Pang, Rui, Wen, Xingzhao, Kang, Yan, Zhang, Zhiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658376/
https://www.ncbi.nlm.nih.gov/pubmed/33230479
http://dx.doi.org/10.1016/j.omtn.2020.10.004