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The Synovium Attenuates Cartilage Degeneration in KOA through Activation of the Smad2/3-Runx1 Cascade and Chondrogenesis-related miRNAs
Knee osteoarthritis (KOA) is a highly prevalent disabling joint disease in aged people. Progressive cartilage degradation is the hallmark of KOA, but its deeper mechanism remains unclear. Substantial evidence indicates the importance of the synovium for joint homeostasis. The present study aimed to...
Autores principales: | Zhao, Xiaoyi, Meng, Fangang, Hu, Shu, Yang, Zibo, Huang, Hao, Pang, Rui, Wen, Xingzhao, Kang, Yan, Zhang, Zhiqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658376/ https://www.ncbi.nlm.nih.gov/pubmed/33230479 http://dx.doi.org/10.1016/j.omtn.2020.10.004 |
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