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LOXL2 Upregulation in Gliomas Drives Tumorigenicity by Activating Autophagy to Promote TMZ Resistance and Trigger EMT

Glioma is the most prevalent primary brain tumor in adults and has an extremely unfavorable prognosis. As a member of the lysyl oxidase (LOX) family, lysyl-oxidase-like-2 (LOXL2) is known to play different roles in different tumors. However, the role of LOXL2 in glioma has not yet been fully elucida...

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Detalles Bibliográficos
Autores principales: Zhang, Qing, Yang, Lianhe, Guan, Gefei, Cheng, Peng, Cheng, Wen, Wu, Anhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658417/
https://www.ncbi.nlm.nih.gov/pubmed/33194658
http://dx.doi.org/10.3389/fonc.2020.569584