In Situ Detection of Adeno-associated Viral Vector Genomes with SABER-FISH

Gene therapy with recombinant adeno-associated viral (AAV) vectors is a promising modality for the treatment of a variety of human diseases. Nonetheless, there remain significant gaps in our understanding of AAV vector biology, due in part to the lack of robust methods to track AAV capsids and genom...

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Detalles Bibliográficos
Autores principales: Wang, Sean K., Lapan, Sylvain W., Hong, Christin M., Krause, Tyler B., Cepko, Constance L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658570/
https://www.ncbi.nlm.nih.gov/pubmed/33209963
http://dx.doi.org/10.1016/j.omtm.2020.10.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658570/
https://www.ncbi.nlm.nih.gov/pubmed/33209963
http://dx.doi.org/10.1016/j.omtm.2020.10.003

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