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In Situ Detection of Adeno-associated Viral Vector Genomes with SABER-FISH
Gene therapy with recombinant adeno-associated viral (AAV) vectors is a promising modality for the treatment of a variety of human diseases. Nonetheless, there remain significant gaps in our understanding of AAV vector biology, due in part to the lack of robust methods to track AAV capsids and genom...
Autores principales: | Wang, Sean K., Lapan, Sylvain W., Hong, Christin M., Krause, Tyler B., Cepko, Constance L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658570/ https://www.ncbi.nlm.nih.gov/pubmed/33209963 http://dx.doi.org/10.1016/j.omtm.2020.10.003 |
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