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Oncolytic Rhabdovirus Vaccine Boosts Chimeric Anti-DEC205 Priming for Effective Cancer Immunotherapy

Prime-boost vaccination employing heterologous viral vectors encoding an antigen is an effective strategy to maximize the antigen-specific immune response. Replication-deficient adenovirus serotype 5 (Ad5) is currently being evaluated clinically in North America as a prime in conjunction with oncoly...

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Detalles Bibliográficos
Autores principales: Tzelepis, Fanny, Birdi, Harsimrat Kaur, Jirovec, Anna, Boscardin, Silvia, Tanese de Souza, Christiano, Hooshyar, Mohsen, Chen, Andrew, Sutherland, Keara, Parks, Robin J., Werier, Joel, Diallo, Jean-Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658579/
https://www.ncbi.nlm.nih.gov/pubmed/33209979
http://dx.doi.org/10.1016/j.omto.2020.10.007