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Heterologous Prime Boost Vaccination Induces Protective Melanoma-Specific CD8(+) T Cell Responses

Cancer vaccination aims at inducing an adaptive immune response against tumor-derived antigens. In this study, we utilize recombinant human adenovirus serotype 5 (rAd5) and recombinant lymphocytic choriomeningitis virus (rLCMV)-based vectors expressing the melanocyte differentiation antigen gp100. I...

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Detalles Bibliográficos
Autores principales: Ring, Sandra S., Królik, Michał, Hartmann, Fabienne, Schmidt, Erika, Ali, Omar Hasan, Ludewig, Burkhard, Kochanek, Stefan, Flatz, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658660/
https://www.ncbi.nlm.nih.gov/pubmed/33209978
http://dx.doi.org/10.1016/j.omto.2020.10.001