Toward a Better Understanding of Bioassays for the Development of Biopharmaceuticals by Exploring the Structure-Antibody-Dependent Cellular Cytotoxicity Relationship in Human Primary Cells

Pharmaceutical manufacturing relies on rigorous methods of quality control of drugs and in particular of the physico-chemical and functional characterizations of monoclonal antibodies. To that end, robust bioassays are very often limited to reporter gene assays and the use of immortalized cell lines...

Descripción completa

Detalles Bibliográficos
Autores principales: Wieckowski, Sébastien, Avenal, Cécile, Orjalo, Arturo V., Gygax, Daniel, Cymer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658677/
https://www.ncbi.nlm.nih.gov/pubmed/33193318
http://dx.doi.org/10.3389/fimmu.2020.552596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658677/
https://www.ncbi.nlm.nih.gov/pubmed/33193318
http://dx.doi.org/10.3389/fimmu.2020.552596

Ejemplares similares