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Severe Impairment of TNF Post-transcriptional Regulation Leads to Embryonic Death

Post-transcriptional regulation mechanisms control mRNA stability or translational efficiency via ribosomes, and recent evidence indicates that it is a major determinant of the accurate levels of cytokine mRNAs. Transcriptional regulation of Tnf has been well studied and found to be important for th...

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Detalles Bibliográficos
Autores principales: Clayer, Elise, Dalseno, Destiny, Kueh, Andrew, Lacey, Derek, Tsai, Minhsuang, Arvell, Elyas H., Wimmer, Verena C., Bouillet, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658709/
https://www.ncbi.nlm.nih.gov/pubmed/33210082
http://dx.doi.org/10.1016/j.isci.2020.101726