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Regulation of PD-L1 expression in K-ras-driven cancers through ROS-mediated FGFR1 signaling
K-ras mutations are major genetic events that drive cancer development associated with aggressive malignant phenotypes, while expression of the immune checkpoint molecule PD-L1 plays a key role in cancer evasion of the immune surveillance that also profoundly affects the patient outcome. However, th...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658718/ https://www.ncbi.nlm.nih.gov/pubmed/33171331 http://dx.doi.org/10.1016/j.redox.2020.101780 |