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What Is the Storage Effect, Why Should It Occur in Cancers, and How Can It Inform Cancer Therapy?

Intratumor heterogeneity is a feature of cancer that is associated with progression, treatment resistance, and recurrence. However, the mechanisms that allow diverse cancer cell lineages to coexist remain poorly understood. The storage effect is a coexistence mechanism that has been proposed to expl...

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Detalles Bibliográficos
Autores principales: Miller, Anna K., Brown, Joel S., Basanta, David, Huntly, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658723/
https://www.ncbi.nlm.nih.gov/pubmed/32723185
http://dx.doi.org/10.1177/1073274820941968