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Prescription Opioid Use and Risk for Major Depressive Disorder and Anxiety and Stress-Related Disorders: A Multivariable Mendelian Randomization Analysis

IMPORTANCE: Growing evidence suggests that prescription opioid use affects depression and anxiety disorders; however, observational studies are subject to confounding, making causal inference and determining the direction of these associations difficult. OBJECTIVE: To investigate the potential bidir...

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Detalles Bibliográficos
Autores principales: Rosoff, Daniel B., Smith, George Davey, Lohoff, Falk W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658804/
https://www.ncbi.nlm.nih.gov/pubmed/33175090
http://dx.doi.org/10.1001/jamapsychiatry.2020.3554