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Prescription Opioid Use and Risk for Major Depressive Disorder and Anxiety and Stress-Related Disorders: A Multivariable Mendelian Randomization Analysis
IMPORTANCE: Growing evidence suggests that prescription opioid use affects depression and anxiety disorders; however, observational studies are subject to confounding, making causal inference and determining the direction of these associations difficult. OBJECTIVE: To investigate the potential bidir...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658804/ https://www.ncbi.nlm.nih.gov/pubmed/33175090 http://dx.doi.org/10.1001/jamapsychiatry.2020.3554 |