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Stem Cell Determinant SOX9 Promotes Lineage Plasticity and Progression in Basal-like Breast Cancer

Lineage plasticity is important for the development of basal-like breast cancer (BLBC), an aggressive cancer subtype. While BLBC is likely to originate from luminal progenitor cells, it acquires substantial basal cell features and contains a heterogenous collection of cells exhibiting basal, luminal...

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Detalles Bibliográficos
Autores principales: Christin, John R., Wang, Chunhui, Chung, Chi-Yeh, Liu, Yu, Dravis, Christopher, Tang, Wei, Oktay, Maja H., Wahl, Geoffrey M., Guo, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658810/
https://www.ncbi.nlm.nih.gov/pubmed/32521267
http://dx.doi.org/10.1016/j.celrep.2020.107742