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Hairpin Oligonucleotide Can Functionalize Gold Nanorods for in Vivo Application Delivering Cytotoxic Nucleotides and Curcumin: A Comprehensive Study in Combination with Near-Infrared Laser

[Image: see text] We prepared a multimodality nanocomplex by functionalizing gold nanorods (GNRs) with a cytotoxic nucleoside, 5-fluoro-2′-deoxyuridine (FdU) containing a DNA hairpin, along with complexation of pleiotropic molecule curcumin. Conjugates were investigated for anti-tumor activity using...

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Detalles Bibliográficos
Autores principales: Das, Upasana, Bhuniya, Avishek, Roy, Anup K., Gmeiner, William H., Ghosh, Supratim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658950/
https://www.ncbi.nlm.nih.gov/pubmed/33195896
http://dx.doi.org/10.1021/acsomega.0c02288