The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice

Protein knockdown using the auxin-inducible degron (AID) technology is useful to study protein function in living cells because it induces rapid depletion, which makes it possible to observe an immediate phenotype. However, the current AID system has two major drawbacks: leaky degradation and the re...

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Detalles Bibliográficos
Autores principales: Yesbolatova, Aisha, Saito, Yuichiro, Kitamoto, Naomi, Makino-Itou, Hatsune, Ajima, Rieko, Nakano, Risako, Nakaoka, Hirofumi, Fukui, Kosuke, Gamo, Kanae, Tominari, Yusuke, Takeuchi, Haruki, Saga, Yumiko, Hayashi, Ken-ichiro, Kanemaki, Masato T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659001/
https://www.ncbi.nlm.nih.gov/pubmed/33177522
http://dx.doi.org/10.1038/s41467-020-19532-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659001/
https://www.ncbi.nlm.nih.gov/pubmed/33177522
http://dx.doi.org/10.1038/s41467-020-19532-z

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