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The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice
Protein knockdown using the auxin-inducible degron (AID) technology is useful to study protein function in living cells because it induces rapid depletion, which makes it possible to observe an immediate phenotype. However, the current AID system has two major drawbacks: leaky degradation and the re...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659001/ https://www.ncbi.nlm.nih.gov/pubmed/33177522 http://dx.doi.org/10.1038/s41467-020-19532-z |