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Complement C6 deficiency exacerbates pathophysiology after spinal cord injury

Historically, the membrane attack complex, composed of complement components C5b-9, has been connected to lytic cell death and implicated in secondary injury after a CNS insult. However, studies to date have utilized either non-littermate control rat models, or mouse models that lack significant C5b...

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Detalles Bibliográficos
Autores principales: Su, Diane, Hooshmand, Mitra J., Galvan, Manuel D., Nishi, Rebecca A., Cummings, Brian J., Anderson, Aileen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659012/
https://www.ncbi.nlm.nih.gov/pubmed/33177623
http://dx.doi.org/10.1038/s41598-020-76441-3