Oxidative stress induced by the anti-cancer agents, plumbagin, and atovaquone, inhibits ion transport through Na(+)/K(+)-ATPase

Oxidative stress inhibits Na(+)/K(+)-ATPase (NKA), the ion channel that maintains membrane potential. Here, we investigate the role of oxidative stress-mediated by plumbagin and atovaquone in the inhibition of NKA activity. We confirm that plumbagin and atovaquone inhibit the proliferation of three...

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Detalles Bibliográficos
Autores principales: Alharbi, Yousef, Kapur, Arvinder, Felder, Mildred, Barroilhet, Lisa, Pattnaik, Bikash R., Patankar, Manish S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659016/
https://www.ncbi.nlm.nih.gov/pubmed/33177587
http://dx.doi.org/10.1038/s41598-020-76342-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659016/
https://www.ncbi.nlm.nih.gov/pubmed/33177587
http://dx.doi.org/10.1038/s41598-020-76342-5

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