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Oxidative stress induced by the anti-cancer agents, plumbagin, and atovaquone, inhibits ion transport through Na(+)/K(+)-ATPase
Oxidative stress inhibits Na(+)/K(+)-ATPase (NKA), the ion channel that maintains membrane potential. Here, we investigate the role of oxidative stress-mediated by plumbagin and atovaquone in the inhibition of NKA activity. We confirm that plumbagin and atovaquone inhibit the proliferation of three...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659016/ https://www.ncbi.nlm.nih.gov/pubmed/33177587 http://dx.doi.org/10.1038/s41598-020-76342-5 |