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Specific populations of urinary extracellular vesicles and proteins differentiate type 1 primary hyperoxaluria patients without and with nephrocalcinosis or kidney stones

BACKGROUND: Primary hyperoxaluria type 1 (PH1) is associated with nephrocalcinosis (NC) and calcium oxalate (CaOx) kidney stones (KS). Populations of urinary extracellular vesicles (EVs) can reflect kidney pathology. The aim of this study was to determine whether urinary EVs carrying specific biomar...

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Detalles Bibliográficos
Autores principales: Jayachandran, Muthuvel, Yuzhakov, Stanislav V., Kumar, Sanjay, Larson, Nicholas B., Enders, Felicity T., Milliner, Dawn S., Rule, Andrew D., Lieske, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659070/
https://www.ncbi.nlm.nih.gov/pubmed/33176829
http://dx.doi.org/10.1186/s13023-020-01607-1