Impact of Chirality and Position of Lysine Conjugation in Triplex-Forming Peptide Nucleic Acids

[Image: see text] Conjugation with cationic lysine residues improves the biophysical and biological properties of peptide nucleic acids (PNAs). A single lysine is routinely used to improve the solubility and prevent aggregation of the neutral and hydrophobic amide backbone of PNA. Literature precede...

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Detalles Bibliográficos
Autores principales: Ryan, Christopher A., Rozners, Eriks
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659144/
https://www.ncbi.nlm.nih.gov/pubmed/33195925
http://dx.doi.org/10.1021/acsomega.0c04021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659144/
https://www.ncbi.nlm.nih.gov/pubmed/33195925
http://dx.doi.org/10.1021/acsomega.0c04021

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