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Impact of Chirality and Position of Lysine Conjugation in Triplex-Forming Peptide Nucleic Acids
[Image: see text] Conjugation with cationic lysine residues improves the biophysical and biological properties of peptide nucleic acids (PNAs). A single lysine is routinely used to improve the solubility and prevent aggregation of the neutral and hydrophobic amide backbone of PNA. Literature precede...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659144/ https://www.ncbi.nlm.nih.gov/pubmed/33195925 http://dx.doi.org/10.1021/acsomega.0c04021 |