Electroporation outperforms in vivo-jetPEI for intratumoral DNA-based reporter gene transfer

Intratumoral delivery of drug-encoding plasmid DNA (pDNA) enables localised in vivo expression of biological drugs, offering an attractive alternative to conventional protein treatment. However, this requires physical or chemical methods to enhance the low transfection efficiency of naked pDNA. Elec...

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Detalles Bibliográficos
Autores principales: Jacobs, Liesl, De Smidt, Elien, Geukens, Nick, Declerck, Paul, Hollevoet, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659317/
https://www.ncbi.nlm.nih.gov/pubmed/33177564
http://dx.doi.org/10.1038/s41598-020-75206-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659317/
https://www.ncbi.nlm.nih.gov/pubmed/33177564
http://dx.doi.org/10.1038/s41598-020-75206-2

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