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Electroporation outperforms in vivo-jetPEI for intratumoral DNA-based reporter gene transfer
Intratumoral delivery of drug-encoding plasmid DNA (pDNA) enables localised in vivo expression of biological drugs, offering an attractive alternative to conventional protein treatment. However, this requires physical or chemical methods to enhance the low transfection efficiency of naked pDNA. Elec...
Autores principales: | Jacobs, Liesl, De Smidt, Elien, Geukens, Nick, Declerck, Paul, Hollevoet, Kevin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659317/ https://www.ncbi.nlm.nih.gov/pubmed/33177564 http://dx.doi.org/10.1038/s41598-020-75206-2 |
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