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Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging

G-protein-coupled receptors (GPCRs) play important roles in cellular functions. However, their intracellular organization is largely unknown. Through investigation of the cannabinoid receptor 1 (CB(1)), we discovered periodically repeating clusters of CB(1) hotspots within the axons of neurons. We o...

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Detalles Bibliográficos
Autores principales: Li, Hui, Yang, Jie, Tian, Cuiping, Diao, Min, Wang, Quan, Zhao, Simeng, Li, Shanshan, Tan, Fangzhi, Hua, Tian, Qin, Ya, Lin, Chao-Po, Deska-Gauthier, Dylan, Thompson, Garth J., Zhang, Ying, Shui, Wenqing, Liu, Zhi-Jie, Wang, Tong, Zhong, Guisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659323/
https://www.ncbi.nlm.nih.gov/pubmed/33177502
http://dx.doi.org/10.1038/s41467-020-19510-5