Monocyte infiltration rather than microglia proliferation dominates the early immune response to rapid photoreceptor degeneration

BACKGROUND: Activation of resident microglia accompanies every known form of neurodegeneration, but the involvement of peripheral monocytes that extravasate and rapidly transform into microglia-like macrophages within the central nervous system during degeneration is far less clear. METHODS: Using a...

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Detalles Bibliográficos
Autores principales: Karlen, Sarah J., Miller, Eric B., Wang, Xinlei, Levine, Emily S., Zawadzki, Robert J., Burns, Marie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659426/
https://www.ncbi.nlm.nih.gov/pubmed/30553275
http://dx.doi.org/10.1186/s12974-018-1365-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659426/
https://www.ncbi.nlm.nih.gov/pubmed/30553275
http://dx.doi.org/10.1186/s12974-018-1365-4

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