Senescence Inflames the Pancreatic Tumor Microenvironment

Pancreatic adenocarcinomas (PDACs) are scarcely vascularized and thus virtually insensitive to chemotherapy and immunotherapy. In a recent issue of Cell, Lowe and collaborators(1) have demonstrated that senescence induction by MEK plus CDK4/CDK6 inhibitors favors PDAC revascularization coupled to in...

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Detalles Bibliográficos
Autores principales: Petroni, Giulia, Galluzzi, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659541/
https://www.ncbi.nlm.nih.gov/pubmed/33205059
http://dx.doi.org/10.1016/j.xcrm.2020.100020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659541/
https://www.ncbi.nlm.nih.gov/pubmed/33205059
http://dx.doi.org/10.1016/j.xcrm.2020.100020

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