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Human Tumor-Infiltrating MAIT Cells Display Hallmarks of Bacterial Antigen Recognition in Colorectal Cancer

Growing evidence indicates a role for the gut microbiota in modulating anti-tumor treatment efficacy in human cancer. Here we study mucosa-associated invariant T (MAIT) cells to look for evidence of bacterial antigen recognition in human colon, lung, and kidney carcinomas. Using mass cytometry and s...

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Detalles Bibliográficos
Autores principales: Li, Shamin, Simoni, Yannick, Becht, Etienne, Loh, Chiew Yee, Li, Naisi, Lachance, Daniel, Koo, Si-Lin, Lim, Teck Por, Tan, Emile Kwong Wei, Mathew, Ronnie, Nguyen, Andrew, Golovato, Justin, Berkson, Julia D., Prlic, Martin, Lee, Bernett, Minot, Samuel S., Nagarajan, Niranjan, Dey, Neelendu, Tan, Daniel S.W., Tan, Iain B., Newell, Evan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659584/
https://www.ncbi.nlm.nih.gov/pubmed/33205061
http://dx.doi.org/10.1016/j.xcrm.2020.100039