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Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids
Although congenital infection by human cytomegalovirus (HCMV) is well recognized as a leading cause of neurodevelopmental defects, HCMV neuropathogenesis remains poorly understood. A major challenge for investigating HCMV-induced abnormal brain development is the strict CMV species specificity, whic...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659592/ https://www.ncbi.nlm.nih.gov/pubmed/33205055 http://dx.doi.org/10.1016/j.xcrm.2020.100002 |