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Wnts regulate planar cell polarity via heterotrimeric G protein and PI3K signaling

In the mammalian cochlea, the planar cell polarity (PCP) pathway aligns hair cell orientation along the plane of the sensory epithelium. Concurrently, multiple cell intrinsic planar polarity (referred to as iPCP) modules mediate planar polarization of the hair cell apical cytoskeleton, including the...

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Detalles Bibliográficos
Autores principales: Landin Malt, Andre, Hogan, Arielle K., Smith, Connor D., Madani, Maxwell S., Lu, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659710/
https://www.ncbi.nlm.nih.gov/pubmed/32805026
http://dx.doi.org/10.1083/jcb.201912071