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The RNA binding protein FMR1 controls selective exosomal miRNA cargo loading during inflammation

Cells respond to inflammatory disease states by releasing exosomes containing highly specific protein and RNA cargos, but how inflammation alters cargo specificity and secretion of exosomes is unknown. We show that increases in exosome secretion induced by either viral infection or LPS/ATP exposure...

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Detalles Bibliográficos
Autores principales: Wozniak, Ann L., Adams, Abby, King, Kayla E., Dunn, Winston, Christenson, Lane K., Hung, Wei-Ting, Weinman, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659717/
https://www.ncbi.nlm.nih.gov/pubmed/32970791
http://dx.doi.org/10.1083/jcb.201912074